Dangerous Liaisons: Long-Term Replication with an Extrachromosomal HPV Genome
Papillomaviruses cause persistent, and usually self-limiting, infections in the mucosal and cutaneous surfaces of the host epithelium.However, in some cases, infection with an oncogenic HPV can lead to cancer.The viral genome is a small, double-stranded circular DNA molecule that is assembled into nucleosomes at all stages of infection.The viral mi